The elderly population has become an important group that increasingly requires special attention with respect to health and social issues. The health of the elderly proceeds on a continuum that begins with the development of symptoms associated with biological changes, and continues to disease onset, functional loss and disability, and ultimately, terminal status and death (Rizzuto and Fratiglioni, 2014). Functional decline in the health of the elderly is associated with increased risk of mortality in terminally ill patients. Hospice care offers a highly humane and cost-effective pathway for end-of-life care (Kang et al., 2012). The purpose of hospice care is not to cure the illness, but to prolong the life expectancy of the patients. Hospice care caters to the psychological and social needs of the elderly in maintaining their quality of life, and their ability to cope with death and bereavement. This care consists of comprehensive protection service programs (Kil, 2004). However, despite the higher quality of life and better pain management that has been observed in hospice patients (Wallston et al., 1988), there is a concern that hospice care might be associated with shortened survival time (Saito et al., 2011). The prediction of life-expectancy for terminal care patients is important both for medical and social reasons, but it is widely recognized as being inaccurate. Life expectancy prediction has both emotional and practical importance for patients, family and medical staff. Patients and their families are able to request the exact information, but the ability of the medical or nursing staff to predict the end-stage of a patient’s life is inadequate (Addington-Hall et al., 1990). Nevertheless, it is necessary to find a predictor of mortality in order to anticipate the life expectancy of the elderly. There are various approaches to increasing the life expectancy of the elderly once death predictors are considered. Predictors of death in the elderly are several and diverse, such as age, loneliness (Perissinotto et al., 2012), Activities of Daily Living (ADL) (Katz et al., 1963; Matzen et al., 2012; Wlodarczyk et al., 2004), recognition (Hirsch et al., 2012), quality of life (Wlodarczyk et al., 2004), physical activity (Jalayondeja et al., 2016), blood albumin (Menon et al., 2005; Sudfeld et al., 2013), and blood transfusion (Chazot et al., 2014). In this study, we investigated the predictors of mortality in elderly individuals, aiming to find ways to help prolong life expectancy. This study is based on data obtained from elderly hospice patients. The analysis of this data provides a meaningful way to explore the health and longevity of the elderly.

Hospice care patients receive basic medical care and observation without special rehabilitation programs to extend life. In this study, there was consistent decrease in the KMMSE & GDS with respect to the time of death, but ADL score was even more affected to the time of death. The risk of death varied in proportion to the scores ranging from low-risk (ADL score 0–1) to high-risk (ADL score 5) groups. Factors such as increasing age, dementia, stroke, and congestive heart failure were associated with higher ADL scores. Physiological measurements, such as low systolic blood pressure and high white blood cell count, were also associated with a higher ADL score (Sood et al., 2011). This suggests that the ADL score on admission captures the effect of both the acute illness and more chronic conditions, and, further, it provides a comprehensive measure of health. Therefore, ADL score is an important a predictor of mortality in the elderly. Obtaining an ADL functional score on admission was simple and easy to perform. Although the ADL score may have overestimated functionality it was strongly predictive of outcomes. This suggests that assessment of ADL score may have a potential role in decision making for the clinical management of frail elderly inpatients (Matzen et al., 2012).

ADL score was associated with blood component values in the present study. As time of death neared, ADL score decreased, and BUN, r-GTP, creatinine rose sharply. Rowe and Kahn (1997) suggested that successful aging has 3 constituent components: avoiding disease and disability, maintaining high cognitive and physical function, and engagement with life. High physical function is a crucial factor for successful aging. Measures of functional performance and physical fitness are important, simple, and objective observations of physical function in elderly. Therefore, physical activity, including exercise is needed to achieve a good ADL score. ADL have proven to be effective in improving the postprandial serum glucose in type 2 diabetic patients, but endurance exercise intensity was even more effective in improving blood sugar homeostasis than daily ADL (van Dijk et al., 2013). Long-term football exercise and strength training helped to effectively maintain the ADL score, develop muscle strength, and prevent functional decline in elderly men (Sundstrup et al., 2016). Fisher et al. (2016) suggested that early mobilization, physical therapy, walking programs, and other approaches may improve mobility in the elderly and potentially reduce hospitalization. Physical exercise and dietary measures are currently the only known ways of slowing the aging process (Le Gall and Ardaillou, 2009). Gremeaux et al. (2012) demonstrated mechanisms that underlie the positive effects of exercise on the aging process. Regular physical activity is associated with a 30% reduction in the risk of cardiovascular mortality in subjects with cardiovascular disease (Nocon et al., 2008). This risk reduction corresponds to 1–2 years of additional life attributable to adequate exercise when compared to individuals who engage in little or no physical activity (Franco et al., 2005). However, the study of exercise intensity for the elderly can be divided into various segments. Xue et al. (2012) suggested that physical activity does not have to be vigorous to be beneficial and that the gain may be the greatest among women who reported the lowest levels of activity. In contrast, Samitz et al. (2011) demonstrated that larger training volume (exercise duration×intensity) is associated with greater reduction in mortality. For a given training volume, engaging in physical activities of a higher intensity provides additional benefit.

According to the statement of the hospital staff, this improvement was related to a correction in dehydration, improved chewing ability, and a drug regimen, among other interventions. As the patient neared death, all functional abilities declined at various rates. Until death, cognitive ability (K-MMSE & GDS) did not decrease as much, but physical functional status and ADL score decreased, and blood component values worsened. In conclusion, ADL scores might be seen as indicators for the delaying of death. Thus, when providing care to those confronted with terminal illness it is important to increase the ADL score. The method to achieve this is to increase physical activity. Consequently, in order to improve ADL score, physical exercise and improved fitness are potential nonpharmacologic means to prevent mortality in the elderly. Using objective data, the present study confirmed some of the clinical reports of medical and nursing staff working in the hospice field; however, further study is needed to construct a model that enables prediction of life-expectancy on the basis of the objective parameters.